CURRICULUM VITAE
Name: Lurdes
Surnames: Patrício Gano
Born: 29-10-1960, Santarém, Portugal
Nationality: Portuguese
Phone: +351-21 994 6195
Fax: +351-21 994 6185
E-mail: lgano (@itn.pt)
Education
2000 – PhD in Pharmaceutical Chemistry, Faculty of Pharmacy, University of Lisbon.
1984 – Graduate in Pharmacy, Faculty of Pharmacy, University of Lisbon.
Professional Employment Career
2000-....... – Researcher, Instituto Tecnológico e Nuclear (ITN).
1990-2000 – Research Assistant, Instituto Tecnológico e Nuclear (ITN).
1985-1990 – Research Trainee, Department of Radioisotopes (LNETI).
Fellowships and Training
Biochemical Separation Methods and Protein Separation, Biotechnology Department, Pharmacia, Uppsala, Sweden.
Radiolabelling of white blood cells at the Institute of Nuclear Medicine of University College and Middlesex School of Medicine, London, UK.
Radiolabelling of monoclonal antibodies with Prof. Stephen Mather at Department of Nuclear Medicine Research, St. Bartholomews Hospital, London, UK.
Cell binding assays and rat biodistribution of CNS radiopharmaceuticals with Dr. Ralf Bergmann at Institut of Bioinorganic and Radiopharmaceutical Chemistry, Rossendorf, Germany.
Membership of Professional Societies
Member of the Sociedade Portuguesa de Medicina Nuclear.
Member of the European Association of Nuclear Medicine.
Main Scientific Area of Research
Radiopharmaceuticals Development.
Other Scientific Areas of Research
Education and Training in Radiopharmacy.
Teaching Activities
Lecturer and national coordinator in the intensive postgraduate course, European Radiopharmacy Course, INSTN, Saclay, France, since 1999.
Collaboration in the Training in Radiopharmacy of Technical Nuclear Medicine Course students, ESTeST, Lisbon.
Invited lecturer on 99mTc-Radiopharmaceuticals, in Pharmacy Course, University of Lisbon.
Participation on the production of a long-distance Radiopharmacy course integrated in the european project Virtual Radiopharmacy – A Mindful Learning Environment (ECShared Cost RTD Action: IST-2001-32291).
Scientific Works
Monograph "Radiofármacos-99mTc – Renais e Hepatobiliares", LNETI, Sacavém (1988).
Monograph "Marcação de Células Sanguíneas", LNETI, Sacavém (1989).
PhD Thesis "Anticorpos e Péptidos Marcados com Tecnécio-99m", Lisbon, 2000.
Original Publications in Refereed Journals and Proceedings of International Conferences (37).
104 Communications to National and International Meetings (43 oral presentations).
Selected Publications
A Bis-(3-hydroxy-4-pyridinone)-EDTA derivative as a Potential Therapeutic Al-Chelating Agent. Synthesis, Metal-Complexation and Biological Assays, M. A. Santos, S. Gama, L. Gano, E. Farkas, J. Inorg Biochem., 99, 1845-1852, 2005.
13- and 14- Membered Macrocyclic Ligands Containing Methylcarboxylate or Methylphosphonate Pendant Arms: Chemical and Biological Evaluation of their 153Sm and 166Ho Complexes as Potential Agents for Therapy or Bone Pain Palliation, F. Marques, L. Gano, M. P. Campello, S. Lacerda, I. Santos, L. M. P. Lima, J. Costa, P. Antunes, R. Delgado, J. Inorg Biochem., 100, 270 2006.
Lymphatic uptake of lipid nanoparticles following endotracheal administration, M.A. Videira, L. Gano, C. Santos, M. Neves, A.J. Almeida, Journal of Microencapsulation, 23,855-862, 2006.
Synthesis and Biological Evaluation of Tricarbonyl Re(I) and Tc(I) Complexes Anchored by Poly(azolyl)borates: Application on the Design of Radiopharmaceuticals for the Targeting of 5-HT1A Receptors, R. Garcia, L. Gano, L. Maria, A. Paulo, I. Santos, H. Spies, J. Biol. Inorg. Chem., 11, 769-782, 2006.
Synthesis and Biodistribution of Two Novel Radioiodinated Areno-annelated Estra-1,3,5(10),16-tetraene-3-ols as Promising Estrogen Receptor Radioligands, M.C. Oliveira, M. Videira, A. Almeida, L. Gano, M. Watanabe, T. Thiemann, A.C. Santos, F. Botelho, C. Oliveira, J. Label Compd. Radiopharm., 49, 559-569, 2006.