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CURRICULUM VITAE

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Name: João Domingos
Surnames: Galamba Correia
Born: 14-10-1967, Porto-Amélia, Mozambique
Nationality: Portuguese

Phone:  351-21 994 6233/1455
E-mail: jgalamba (@itn.pt)

Education

  • 1998-2000 – FCT/PRAXIS fellowship: Postdoctoral position at the Inorganic and Radiopharmaceutical chemistry group, Department of Chemistry, Instituto Tecnológico e Nuclear, Sacavém, Portugal.

  • 1993-1996 – PhD in Inorganic Chemistry at the Inorganic Chemistry Institute of the Technical University of Munich, Germany, under the Supervision of Prof. Dr. Drs. hc. W. A. Herrmann. Title of the Thesis: Molecular Rhenium Oxides as Oxidation Catalysts.

  • 1985-1991 – Graduation in Pharmaceutical Sciences, Faculdade de Farmácia, Universidade de Lisboa, Portugal.

Professional Employment Career

  • 02/2006 – Principal Researcher, ITN.

  • 2000 – Invited Junior Researcher, Inorganic and Radiopharmaceutical Chemistry Group, Instituto Tecnológico e Nuclear (ITN).

  • 1999 – Pharmaceutical Assessor (Radiopharmaceuticals - Quality), at the National Portuguese Authority for the Evaluation of Medicinal Products (INFARMED).

  • 1996-1997 – Pharmacist at Sanofi-Winthrop, Portugal.

Fellowships and Training

  • 2003 – STSM (short term scientific mission) at the Division of Radiological Chemistry, Institute of Nuclear Medicine, Department of Radiology, University Hospital, Basel, Switzerland in the group of Prof. H. Maecke - COST ACTION B12. Radiotracers for in vivo assessment of biological functions. Working Group 3: "RADIOLABELLED BIOLOGICALLY ACTIVE PEPTIDES".

  • 2001 – STSM (short term scientific mission) at the Institute of Inorganic Chemistry, University of Zurich, Switzerland, in the group of Prof. R. Alberto - COST ACTION B12. Radiotracers for in vivo assessment of biological functions. Working Group 5: "TECHNETIUM CHELATES".

  • 2000 – STSM (short term scientific mission) at the Institute of Inorganic Chemistry, University of Zurich, Switzerland, in the group of Prof. R. Alberto - COST ACTION B12. Radiotracers for in vivo assessment of biological functions. Working Group 5: "TECHNETIUM CHELATES"

  • 1994/1996 – DAAD fellowship at the Inorganic Chemistry Institute of the Technical University of Munich, Germany.

  • 1993 – Four months training at the Inorganic Chemistry Institute of the Technical University of Munich, Germany under the supervision of Prof. Dr. Drs. hc. W. A. Herrmann.

  • 1991/1993 – JNICT fellowship at the Organic Chemistry group of the Instituto de Tecnologia Química e Biológica, Oeiras, Portugal.

  • 1990/1991 – Undergraduate Trainee at the Pfizer laboratories, Portugal.

  • 1988/1990 – INIC undergraduate fellowship at the Centro de Estudos de Ciências Farmacêuticas, Universidade de Lisboa.

Membership of Professional Societies

  • Member of the Ordem dos Farmacêuticos, Portugal.

  • Member of the Sociedade Portuguesa de Medicina Nuclear.

Scientific Specialization

  • Organic Chemistry.

  • Inorganic Chemistry. Homogeneous Oxidation catalysis.

Other Scientific Areas of Research

  • Medicinal Chemistry.

  • Labeling of relevant Biomolecules with 99mTc/Re.

Teaching Activities (Lecturer)

  • MSc in Química Inorgânica Biomédica - Aplicações em Diagnóstico e Terapia - Faculdade de Ciências, Universidade de Lisboa/ITN.

  • MSc in Química Farmacêutica e Terapêutica - Faculdade de Farmácia, Universidade de Lisboa.

Participation in Projects

  • POCI/SAU-FCF/58855/2004: Radiolabeling of L-Arginine Analogues with the Unit fac-[99mTc(CO)3]+ for Probing Nitric Oxide Synthase (NOS) in vivo: Synthesis, Characterization and Biological Evaluation (2005-2008).

  • Specific Organometallic Complexes, Research Contract Mallinckrodt - Tyco Healthcare (2003-2006).

  • Development of 99mTc based small biomolecules using novel 99mTc Cores, IAEA project (2002-2005).

  • COST B12: Radiotracers for in vivo Assessment of Biological Functions (1999-2004).

  • POCTI/QUI/35423/2000: Complexos de Re e Tc para Radiofármacos Específicos para Receptores de Péptidos: Química, Radioquímica e Estudos Biológicos in vitro e in vivo (2001-2004).

Scientific Works

  • PhD Thesis: "Molecular Rhenium Oxides as Oxidation Catalysts".

  • 6 Original patents.

  • 25 Original publications in Refereed Journals.

  • 28 Communications to National and International Meetings.

  • POSTER PRICE in the session "Technetium, Rhenium and other metals" at the 14th International Symposium on Radiopharmaceutical Chemistry (ISRC), June 10-15, 2001, Interlaken, Switzerland: Heterofunctionalized Phosphines as Anchor Groups for Coupling Biomolecules to the fac-[M(CO)3]+ (M=Re, Tc) Moiety, J. D. G. Correia, I. Santos, R. Alberto, K. Ortner, H. Spies, A. Drews.

Selected Publications

  • Pyrazolyl Conjugates of Bombesin: A New Tridentate Ligand Framework for Stabilization of the fac-[M(CO)3]+ Moiety, S. Alves, J. D. G. Correia, I. Santos, B. Veerendra, G. L. Sieckman, T. J. Hoffman, T. Rold, L. Retzloff, J. McCrate1, A. Prasanphanich, C. J. Smith, Nucl. Med. Biol. 2006, in press.

  • Dramatic Effect of the Tridentate Ligand on the Stability of the 99mTc "3+1" Oxocomplexes Bearing Arylpiperazine Derivatives, C. Fernandes, J. D. G. Correia, L. Gano, I. Santos, S. Seifert, R. Syhre, R. Bergmann, H. Spies, Bioconjugate Chem. 2005, 16(3), 660-668.

  • Pyrazolyl Derivatives as Bifunctional Chelators for Labeling Tumor-Seeking Peptides with the fac-[M(CO)3]+ Moiety (M=99mTc, Re): Synthesis, Characterization and Biological Behaviour, S. Alves, A. Paulo, J. D. G. Correia, L. Gano, C. J. Smith, I. Santos, Bioconjugate Chem. 2005, 16(2), 438-449.

  • Rhenium and Technetium Complexes Anchored by Phosphines and Scorpionates for Radiopharmceutical Applications (Review), I. Santos, A. Paulo, J. D. G. Correia, Topics in Current Chemistry 2005, 252, 45-84.

  • A Short Ride on Scorpionates: From d- to f-elements (Review), A. Paulo, J. D. G. Correia, M. P. C. Campello, I. Santos, Polyhedron 2004, 23 (2-3), 331-360.

  • Rhenium and Technetium Tricarbonyl Complexes Anchored by 5-HT1A Receptor-Binding Ligands Containing P,O/N Donor Atom Sets, E. Palma, J. D. G. Correia, Â. Domingos, I. Santos, R. Alberto, H. Spies, J. Organomet. Chem. 2004, 689, 4811-4819.

  • Rhenium(I)- and Technetium(I)Tricarbonyl Complexes anchored by Bifunctional Pyrazole-Diamine and Pyrazole-Dithioether chelators, R. F. Vitor, S. Alves, J.D.G. Correia, A. Paulo, I. Santos, J. Organomet. Chem. 2004, 689, 4764-4774.

Original Patents

  • Bifunctional Tridentate Pyrazolyl Containing Ligands for Re and Tc Tricarbonyl complexes, I. Santos, J. D. G. Correia, A. Paulo, S. Alves, R. Vitor, WO 2004/091669 A1, 2004-10-28.

  • Process for the selective oxidation of aromatic compounds, W. A. Herrmann, J. D. G. Correia, R. W. Fischer, US 5,710,292, 1998-01-20.

  • Process for the catalytic oxidation of aromatic compounds, W. A. Herrmann, J. D. G. Correia, R. W. Fischer, W. Adam, J. Lin, C. R. Saha-Möller, M. Shimizu, US 5,616,734, 1997-04-01.

  • Verfahren zur katalytischen Oxidation von Aromatischen Verbindungen, W. A. Herrmann, J. D. G. Correia, R. W. Fischer, W. Adam, J. Lin, C. R. Saha-Möller, M. Shimizu, EP 0 665 209 A1, 1995-01-24.

  • Verfahren zur selektiven Oxidation aromatischer Verbindungen, W. A. Herrmann, J. D. G. Correia, R. W. Fischer, EP 0 686 618 A1, 1995-05-26.

  • Verfahren zur katalytischen Oxidation von Aromatischen Verbindungen, W. A. Herrmann, J. D. G. Correia, R. W. Fischer, W. Adam, J. Lin, C. R. Saha-Möller, M. Shimizu, DE 44 19 799 A1, 1995-12-07.

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