Ícone: Impressão reduzida.  Print

CURRICULUM VITAE

António Paulo photo.

Name: António Manuel
Surnames: Rocha Paulo
Born: 3-06-1962, Bencatel, Portugal
Nationality: Portuguese

Phone: +351-21 994 6196
Fax: +351-21 994 6185
E-mail: apaulo (@itn.pt)

Education

  • 1998 – PhD in Chemistry at Instituto Superior Técnico (IST) of the Technical University of Lisbon, with Doctor Isabel Rego dos Santos.

  • 1986 – Graduate in Chemical Engineering, Instituto Superior Técnico (IST) of the Technical University of Lisbon.

Professional Employment Career

  • 02/2006 – Principal Researcher, ITN.
  • Since 1998 – Auxiliary Researcher, ITN.
  • 1992-1998 – Research Assistant, ITN.
  • 1989-1992 – Research Trainee, Instituto Tecnológico e Nuclear (ITN), Sacavém, Portugal.

Fellowships and Training

  • 10/03-16/03/1995 – Easter School on Radiopharmaceuticals, Liverpool/ England.

  • 01/02-30/09/1991 – Training at the Institut für Heisse Chemie, with Professor Basil Kanellakopulos.

  • 1986-1988  – INETI/ICEN fellowship: Departamento de Radioisótopos of Instituto Ciência e Energia Nuclear (ICEN), with Doctor Maria dos Anjos Neves.

Membership of Professional Societies

  • Member of the Sociedade Portuguesa de Química.

Scientific Specialization

  • Inorganic and Organometallic Chemistry.

Other Scientific Areas of Research

  • Radiopharmaceutical Development.

Teaching Activities

  • Since 2004 – Teaching Radiochemistry and Inorganic Chemistry in the Master Course on Biomedical Inorganic Chemistry: Diagnostic and Therapeutical Applications, ITN/FCCUL.

  • Since 2000 – Teaching Radiopharmacy in the Technical Nuclear Medicine Course, ESTeSL-Lisbon.

Participation in Projects

  • POCI/QUI/57632/2004: Multicomponent Technetium and Gallium Metallointercalators for Targeted Radiotherapy, (since October 2005).

  • POCI/QUI/59588/2004: Novel Radioactive Probes for Molecular Imaging of Sigma Receptors, (since October 2005).
  • POCTI/2001/QUI/42939: Organometallic Rhenium and Technetium Complexes: Design of Radiopharmaceuticals for Brain Receptor Imaging, (March 2002-February 2005).

Scientific Works

  • PhD Theses "Oxo-Complexos e Polihidretos de Rénio com Boratos Poli(pirazolilo)", IST-UTL (1998).

  • Monograph "Química de Radiofármacos: A- Monofosfonatos de tecnécio (99mTc/99Tc); B- Marcação de MIBG com 131I na forma de kit liofilizado", LNETI-Sacavém (1991).

  • Monograph "Química de Tecnécio: Aspectos relevantes em radiofármacos", LNETI-Sacavém (1991).

  • 30 Original Publications in Refereed Journals.

  • 42 Communications to National and International Meetings.

Selected Publications

  • Tris(pyrazolyl)methane 99mTc tricarbonyl complexes for myocardial imaging, L. Maria, C. Fernandes, R. Garcia, L. Gano, A. Paulo, I. C. Santos, Isabel Santos, Dalton Trans., 2009, 603–606.

  • Pyrazolyl-Diamine Ligands That Bear Anthracenyl Moieties and Their Rhenium(I) Tricarbonyl Complexes: Synthesis, Characterization and DNA-Binding Properties, R. F. Vitor, I. Correia, M. Videira, F. Marques, A. Paulo, J, C. Pessoa, G. Viola, G. G. Martins, I. Santos, ChemBioChem 2008, 9 (1) 131-142.

  • Very Small and Soft Scorpionates: Water Stable Technetium Tricarbonyl Complexes Combining a Bis-agostic (k3-H, H, S) Binding Motif with Pendant and Integrated Bioactive Molecules, L. Maria, A. Paulo, I. C. Santos, I. Santos, P. Kurz, B. Spingler, R. Alberto, J. Am. Chem. Soc. 2006, 128, 14590-14598

  • Synthesis and Biological Evaluation of Tricarbonyl Re(I) and Tc(I) Complexes Anchored by Poly(azolyl)borates: Application on the Design of Radiopharmaceuticals for the Targeting of 5-HT1A Receptors, R. Garcia, L. Gano, L. Maria, A. Paulo, Isabel Santos e H. Spies, J. Biol. Inorg. Chem. 2006, 11, 769-782.

  • Pyrazolyl Containing Ligands as Bifunctional Chelators for Labelling Biomolecules with the fac-[M(CO)3]+ Moiety (M=99mTc, Re): Synthesis, Characterization and Biological Behaviour, S. Alves, J. D. G. Correia, A. Paulo, L. Gano, J. Smith e I. Santos, Bioconjugate Chemistry 2005, 16, 438-449.

Page back